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Mixtures of multiple allergens for use in the clinical diagnosis of allergic conditions. Patients are exposed to molecular components of broad allergen groups, and their IgE antibody levels are measured to determine sensitization to related allergen groups.
An antiparasitic compound and a derivative of artemisinin; induces mortality in adult wild-type and pfatp6-mutant P. falciparum but the efficacy is decreased in the mutants (IC50s = 8.2 and 13.5 nM, respectively); reduces parasitemia in P. falciparum-infected monkeys and P. berghei-infected mice (CD50s = 7.1 and 55 mg/kg, respectively); reduces the worm burden of S. mansoni trematodes in mice at doses ranging from 200-500 mg/kg
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Reagents support EliA, an enzyme immunoassay to measure autoantibodies for the diagnosis of autoimmune diseases such as rheumatoid arthritis, celiac disease or systemic lupus erythematosus.